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5-aMino-6-Methyl-3-Pyridinecarboxylic acid ethyl ester CAS:1008138-73-5
ZhonghanProduct Overview
5-Amino-6-methylnicotinate is an organic compound of great value, with a molecular formula of C9H12N2O2 and a molecular weight of about 180.20. From the perspective of chemical structure, it is a derivative of nicotinate ethyl ester, with amino and methyl groups introduced at specific positions of the pyridine ring, giving the compound unique chemical properties and reactivity. In appearance, it usually appears as a white to off-white crystalline powder, which makes it relatively stable during storage and transportation and easy to handle.
ZhonghanStructural formula
Molecular formula |
C9H12N2O2 |
Molecular weight |
180.2 |
Boiling point |
327.9±37.0 °C (Predicted) |
Density |
1.158±0.06 g/cm3 (Predicted) |
Storage conditions |
under inert gas (nitrogen or Argon) at 2–8 °C |
Acidity coefficient (pKa) |
4.95±0.20 (Predicted) |
ZhonghanPhysical properties
1. Appearance and properties: Usually white to off-white crystalline powder with a certain regular crystal shape;
2. Melting point: It has a melting point value, which can be supplemented according to actual measurements. The melting point is relatively stable and reflects the characteristics of its intermolecular forces and crystal structure to a certain extent;
3. Solubility: Slightly soluble in water, which is due to the combined effect of the hydrophilic amino group and the less polar ester group, methyl group and other groups in its molecular structure. However, it is soluble in common organic solvents such as ethanol, dichloromethane, acetone, etc., and can be well dispersed and participate in chemical reactions in organic solvents;
4. Stability: It is relatively stable in a dry, light-proof environment at room temperature and pressure. However, under strong acidic or alkaline conditions, hydrolysis may occur, resulting in the destruction of the molecular structure; there is also a risk of oxidation when in contact with strong oxidants.
ZhonghanApplication Areas
1. Drug synthesis intermediates: Because of the active amino and ester groups in its molecular structure, it has become an important intermediate for the synthesis of a variety of drugs. For example, it can be used to synthesize nitrogen-containing heterocyclic drugs with specific biological activities, and plays a key role in the research and development and production of antibacterial, antiviral, anti-tumor drugs. Through further chemical modification of its amino and ester groups, different functional groups can be introduced, thereby changing the activity, selectivity and pharmacokinetic properties of the drug;
2. Materials Science: In the preparation of some new organic materials, 5-amino-6-methylnicotinic acid ethyl ester can also be used as an important structural unit. Its unique chemical structure gives the material special optical and electrical properties, and can be used in the fields of organic optical materials, sensor materials, etc.